2013 Nucleic Acid Purification Dashboard Series…

2013 Nucleic Acid Purification Dashboard Series 1 – China -

Catalog number: 1302NPC
Publication date: April 2013
Company-wide electronic copy: $3,975

Please enquire about single-user* electronic copy pricing

*single-user pricing is intended for small companies, of 40 or less employees. Please order these copies directly with Percepta Associates.

Overview

Introduction

Nucleic acid purification is one of the few basic methods ubiquitous among scientists using molecular biology techniques to investigate processes such as gene expression, genetic diversity, protein function and molecular interactions. The Nucleic Acid Purification Dashboard was developed from responses to a 25-question survey of 449 scientists predominantly located in China. This Dashboard reveals key market indicators for the nucleic acid purification market as a whole as well as for the following 15 sub-segments:

Gel Extraction
Post-Reaction Cleanup (i.e. PCR, enzyme digestion)
Plasmid DNA Miniprep (1-2 ml culture)
Plasmid DNA Midiprep (5-50 ml culture)
Plasmid DNA Maxiprep (100 ml culture or more)
Genomic DNA from cells or tissue
Genomic DNA from whole blood
Genomic DNA from FFPE tissue
DNA Library Preparation for Next Generation Sequencing
RNA Library Preparation for Next Generation Sequencing
Total RNA from cells or tissue
Total RNA from whole blood
Total RNA from FFPE tissue
mRNA
microRNA

Consistent with the previous series of Nucleic Acid Purification Dashboards™ for North America and Europe, Percepta has launched the first in the series of Nucleic Acid Purification Dashboards™ for the Chinese market. This 2013 Dashboard provides a snapshot of the current Chinese nucleic acid purification market landscape, to establish a foundation of data to which future series of Life Science Dashboard can be compared.

Survey Methodology

In January of 2013, Percepta fielded the Nucleic Acid Purification Survey to a panel of Chinese life science researchers. Individuals were invited by e-mail to click through to a webpage at perceptabioanalytix.com where the survey was hosted. Invitations were delivered on January 20, 2013 and results collected through February 1, 2013. A total of 449 scientists participated in the survey, of which 401 are actively engaged in performing Nucleic Acid Purification. Results based on the aggregate of collected responses are revealed in this Nucleic Acid Purification Dashboard.

Respondent Demographics

Respondents from different market segments are well represented. 78.1% of the respondents are employed in academic/non-profit organizations, while 21.9% work in an industrial setting.

Respondents from different geographic regions are well presented. 43.9% of respondents are from North China, and 30.9% reside in East China, which are China’s most developed regions with outstanding scientific research, education and high-tech industries.

Junior, mid-level and senior scientists are well represented in the data set, with the most cited job titles being Graduate Students/Medical Students/Student (37.7% of respondents) and Lab Technician/ Research Assistant/Research Associate (17.5%). A wide variety of scientific areas of specialization is also evident, led by Molecular Biology (indicated by 64.3% of respondents as their area of expertise), Biochemistry (56.6%) and Cell Biology (36.9%).

Small (1 to 5 scientists), mid-size (6 to 10 scientists) and large laboratories (>10 scientists) are well represented in the respondent data set. A total of 12.4% of survey participants work in labs where one to five people perform experiments. 26.4% are employed in labs with six to ten scientists, while the remaining 61.1% of respondents work in labs where greater than 10 individuals work at the bench.

31.4% of respondents indicated that 1 to 5 people in their laboratories perform nucleic acid purification experiments at least a few times each year. An additional 28.7% of survey participants indicated that 6 to 10 individuals perform nucleic acid purification experiments in their laboratories at least a few times per year. 39.9% of respondents work in labs where greater than 10 people perform nucleic acid purification experiments at least a few times each year.

The three most common primary organisms that scientists work with when performing nucleic acid purification are: human (indicated by 31.7% of respondents), bacteria (24.7%) and mouse (15.0%).

6 Figures and Tables
12 Executive Summary
14 Nucleic Acid Purification Dashboard “At A Glance”
17 Market Opportunity Matrix
19 Qualification and Demographics
24 Frequency of Performance of Life Science Techniques
27 Frequency of Performance of NAP Methods
62 Use of Commercial Reagents and Format Preference
69 Co-Promotion of NAP Methods and Life Science Techniques
74 Throughput/Usage Rates, Market Growth Rates and Stated Price
81 Market Segment Sizes, Total Market Size and Total Market Growth Rate
83 Market Shares by Segment (Share of Mentions)
132 Purchase and Distribution
138 Customer Satisfaction and Interest in Switching Suppliers
143 Important Product Features That Influence Purchasing Decisions
146 Primary and Secondary Downstream Applications
179 Desired Changes to NAP Products
189 Appendix

Figures and Tables

20 Figure 1: Qualification – Frequency of NAP Performance
21 Figure 2: Summary of Demographics
22 Figure 3: Primary and Secondary Species Focus
25 Figure 4: Percent Performing Various Life Science Techniques at Least a Few Times per Year
29 Figure 5: Percent Performing Various NAP Methods at Least a Few Times per Year
32 Figure 6: Frequency of Performing Gel Extraction
34 Figure 7: Frequency of Performing Post-Reaction Cleanup
36 Figure 8: Frequency of Performing Plasmid DNA Miniprep Purification
38 Figure 9: Frequency of Performing Plasmid DNA Midiprep Purification
40 Figure 10: Frequency of Performing Plasmid DNA Maxiprep Purification
42 Figure 11: Frequency of Performing Genomic DNA Isolation from Cells or Tissue
44 Figure 12: Frequency of Performing Genomic DNA Isolation from Whole Blood
46 Figure 13: Frequency of Performing Genomic DNA Isolation from FFPE Tissue
48 Figure 14: Frequency of Performing DNA Library Preparation for NGS
50 Figure 15: Frequency of Performing RNA Library Preparation for NGS
52 Figure 16: Frequency of Performing Total RNA Isolation from Cells or Tissue
54 Figure 17: Frequency of Performing Total RNA Isolation from Whole Blood
56 Figure 18: Frequency of Performing Total RNA Isolation from FFPE Tissue
58 Figure 19: Frequency of Performing mRNA Isolation
60 Figure 20: Frequency of Performing microRNA Isolation
66 Figure 21: Preference for NAP Reagent Formats
88 Figure 22: Primary Suppliers of Gel Extraction Products
91 Figure 23: Primary Suppliers of Post-Reaction Cleanup Products
94 Figure 24: Primary Suppliers of Plasmid DNA Miniprep Purification Products
97 Figure 25: Primary Suppliers of Plasmid DNA Midiprep Purification Products
100 Figure 26: Primary Suppliers of Plasmid DNA Maxiprep Purification Products
103 Figure 27: Primary Suppliers of Genomic DNA Isolation (from Cells or Tissue) Products
106 Figure 28: Primary Suppliers of Genomic DNA Isolation (from Whole Blood) Products
109 Figure 29: Primary Suppliers of Genomic DNA Isolation (from FFPE Tissue) Products
112 Figure 30: Primary Suppliers of DNA Library Preparation (for NGS) Products
115 Figure 31: Primary Suppliers of RNA Library Preparation (for NGS) Products
117 Figure 32: Primary Suppliers of Total RNA Isolation (from Cells or Tissue) Products
120 Figure 33: Primary Suppliers of Total RNA Isolation (from Whole Blood) Products
123 Figure 34: Primary Suppliers of Total RNA Isolation (from FFPE Tissue) Products
126 Figure 35: Primary Suppliers of mRNA Isolation Products
129 Figure 36: Primary Suppliers of microRNA Isolation Products
134 Figure 37: Primary Purchase Methods
137 Figure 38: Top Sales Agents/Distributors by Share of Mention
140 Figure 39: Percent Satisfaction with Current NAP Product – No Interest in Switching to a Different Supplier
142 Figure 40: Recent History of Switching (Last 6 Months)
145 Figure 41: Most Important Features
149 Figure 42: Primary & Secondary Applications for Purified Gel Extraction Product
151 Figure 43: Primary & Secondary Applications for Purified Post-Reaction Cleanup Product
153 Figure 44: Primary & Secondary Applications for Purified Miniprep Plasmid DNA
155 Figure 45: Primary & Secondary Applications for Purified Midiprep Plasmid DNA
157 Figure 46: Primary & Secondary Applications for Purified Maxiprep Plasmid DNA
159 Figure 47: Primary & Secondary Applications for Purified Genomic DNA from Cells and Tissue
161 Figure 48: Primary & Secondary Applications for Purified Genomic DNA from Whole Blood
163 Figure 49: Primary & Secondary Applications for Purified Genomic DNA from FFPE Tissue
165 Figure 50: Primary & Secondary Applications for Purified DNA Library for NGS
167 Figure 51: Primary & Secondary Applications for Purified RNA Library for NGS
169 Figure 52: Primary & Secondary Applications for Purified Total RNA from Cells or Tissue
171 Figure 53: Primary & Secondary Applications for Purified Total RNA from Whole Blood
173 Figure 54: Primary & Secondary Applications for Purified Total RNA from FFPE Tissue
175 Figure 55: Primary & Secondary Applications for Purified mRNA
177 Figure 56: Primary & Secondary Applications for Purified microRNA
180 Figure 57: Desired Changes to NAP Products
26 Table 1: Frequency of Performing Various Life Science Techniques
30 Table 2: Percent Performing Various NAP Methods
31 Table 3: Summary of Frequency of Performing Various NAP Methods
33 Table 4: Frequency of Performing Gel Extraction
35 Table 5: Frequency of Performing Post-Reaction Cleanup
37 Table 6: Frequency of Performing Plasmid DNA Miniprep Purification
39 Table 7: Frequency of Performing Plasmid DNA Midiprep Purification
41 Table 8: Frequency of Performing Plasmid DNA Maxiprep Purification
43 Table 9: Frequency of Performing Genomic DNA Isolation from Cells or Tissue
45 Table 10: Frequency of Performing Genomic DNA Isolation from Whole Blood
47 Table 11: Frequency of Performing Genomic DNA Isolation from FFPE Tissue
49 Table 12: Frequency of Performing DNA Library Preparation for NGS
51 Table 13: Frequency of Performing RNA Library Preparation for NGS
53 Table 14: Frequency of Performing Total RNA Isolation from Cells or Tissue
55 Table 15: Frequency of Performing Total RNA Isolation from Whole Blood
57 Table 16: Frequency of Performing Total RNA Isolation from FFPE Tissue
59 Table 17: Frequency of Performing mRNA Isolation
61 Table 18: Frequency of Performing microRNA Isolation
64 Table 19: Percent Use of Commercial NAP Reagents
65 Table 20: Preference for NAP Reagent Formats (Academia/Non-Profit Vs. Industry)
71 Table 21: Co-Promotion Opportunities (of Life Science Techniques with NAP Methods)
72 Table 22: Co-Promotion Opportunities (of NAP Methods with Life Science Techniques)
73 Table 23: Co-Promotion Opportunities (of NAP Methods)
76 Table 24: Median, Mean and Trim Mean Monthly Throughput
77 Table 25: Median, Mean and Trim Mean Monthly Throughput (Academia/Non- Profit Vs. Industry)
78 Table 26: Numbers of Isolations Performed per Month
79 Table 27: Projected Growth Rates for Various Nucleic Acid Purification Methods
80 Table 28: Median, Mean and Trim Mean Price Per Isolation
82 Table 29: Estimated 2013/2014 Chinese Market Size for NAP Products
85 Table 30: Market Share Leaders (Share of Mentions)
89 Table 31: Primary Suppliers of Gel Extraction Products
92 Table 32: Primary Suppliers of Post-Reaction Cleanup Products
95 Table 33: Primary Suppliers of Plasmid DNA Miniprep Purification Products
98 Table 34: Primary Suppliers of Plasmid DNA Midiprep Purification Products
101 Table 35: Primary Suppliers of Plasmid DNA Maxiprep Purification Products
104 Table 36: Primary Suppliers of Genomic DNA Isolation (from Cells or Tissue) Products
107 Table 37: Primary Suppliers of Genomic DNA Isolation (from Whole Blood) Products
110 Table 38: Primary Suppliers of Genomic DNA Isolation (from FFPE Tissue) Products
113 Table 39: Primary Suppliers of DNA Library Preparation (for NGS) Products
116 Table 40: Primary Suppliers of RNA Library Preparation (for NGS) Products
118 Table 41: Primary Suppliers of Total RNA Isolation (from Cells or Tissue) Products
121 Table 42: Primary Suppliers of Total RNA Isolation (from Whole Blood) Products
124 Table 43: Primary Suppliers of Total RNA Isolation (from FFPE Tissue) Products
127 Table 44: Primary Suppliers of mRNA Isolation Products
130 Table 45: Primary Suppliers of microRNA Isolation Products
141 Table 46: Satisfaction with NAP Product and Reasons for Dissatisfaction
148 Table 47: Summary of Primary Downstream Applications

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